Welcome to the HBVdb home page !

The specialized Hepatitis B Virus (HBV) database, HBVdb, allows the researchers to investigate the genetic variability of the virus and the viral resistance to treatment. HBV is a major health problem worldwide with more than 350 million individuals being chronically infected. The main drugs used to treat infected patients are nucleos(t)ides analogs (reverse transcriptase inhibitors). Unfortunately, HBV mutants resistant to these drugs may be selected and be responsible for treatment failure. HBVdb contains a collection of computer-annotated sequences based on manually annotated reference genomes. The database web interface allows static and dynamic queries and provides integrated analysis tools including sequence annotation, genotyping and drug resistance profiling.

The current HBVdb release is 57.0 with 105229 entries and was last updated on 2022-12-07 (see news).

The HBVdb service has been accessed 324105 times by 34307 unique users since 2012 (see statistics).

If you use HBVdb in your work, please cite Hayer J. et al., Nucleic Acids Research, 2013 (see about).

Please use the menu bar above or the submit buttons below in order to access the Hepatitis B Virus Database (HBVdb) resources. A brief description of each resource will appear when the pointing device pauses over a menu or a button. You can find more explanations about how to use these resources in the help page from the HBVdb menu (see help).

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